Chondrocyte expressed protein-68 (CEP-68), a novel human marker gene for cultured chondrocytes.

نویسندگان

  • E Steck
  • K Benz
  • H Lorenz
  • M Loew
  • T Gress
  • W Richter
چکیده

In the search for new marker genes suitable to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture, we have identified and characterized a novel gene called chondrocyte expressed protein-68 (CEP-68), harbouring an N-terminal leader peptide and an epidermal growth factor-like calcium-binding domain. CEP-68 defines a new family of proteins and complements collagen type II as a new marker for stem-cell-based chondrogenic tissue engineering.

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عنوان ژورنال:
  • The Biochemical journal

دوره 353 Pt 2  شماره 

صفحات  -

تاریخ انتشار 2001